Gene

frmd6

ID

ZDB-GENE-050522-354

Name

FERM domain containing 6

Symbol

frmd6 Nomenclature History

Previous Names

wu:fb38g08 (1)
zgc:110114 (1)

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to be involved in positive regulation of hippo signaling. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasmic side of apical plasma membrane. Orthologous to human FRMD6 (FERM domain containing 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110114 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With frmd6 Human Ortholog

No data available

Associated With frmd6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000299	FERM domain
Domain	IPR018979	FERM, N-terminal
Domain	IPR018980	FERM, C-terminal PH-like domain
Domain	IPR019748	FERM central domain
Domain	IPR019749	Band 4.1 domain
Domain	IPR041781	FERM domain-containing protein 6, FERM domain C-lobe
Family	IPR047145	FERM domain-containing protein 6-like
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR014352	FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR035963	FERM superfamily, second domain

Domain Details Per Protein

Protein	Length	Band 4.1 domain	FERM/acyl-CoA-binding protein superfamily	FERM central domain	FERM, C-terminal PH-like domain	FERM domain	FERM domain-containing protein 6, FERM domain C-lobe	FERM domain-containing protein 6-like	FERM, N-terminal	FERM superfamily, second domain	PH-like domain superfamily	Ubiquitin-like domain superfamily
UniProtKB:Q503U6 InterPro	616

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	frmd6-201 (1) Ensembl	Ensembl	2,353 nt	Select Tool ZFIN BLAST
mRNA	frmd6-202 (1) Ensembl	Ensembl	766 nt	Select Tool ZFIN BLAST
mRNA	frmd6-203 (1) Ensembl	Ensembl	4,563 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations