Gene
fign
- ID
- ZDB-GENE-050522-339
- Name
- fidgetin
- Symbol
- fign Nomenclature History
- Previous Names
-
- zgc:110229
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable ATP hydrolysis activity and microtubule severing ATPase activity. Predicted to be involved in anatomical structure morphogenesis. Predicted to act upstream of or within cell division. Predicted to be located in cytoplasm; microtubule cytoskeleton; and nuclear matrix. Is expressed in lens placode; nervous system; solid lens vesicle; and somite. Orthologous to human FIGN (fidgetin, microtubule severing factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110229 (18 images)
- eu950 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR015415 | Spastin/Vps4, C-terminal |
| Domain | IPR047828 | Fidgetin, ATPase domain |
| Family | IPR050304 | Microtubule-severing AAA ATPase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | ATPase, AAA-type, core | Fidgetin, ATPase domain | Microtubule-severing AAA ATPase | P-loop containing nucleoside triphosphate hydrolase | Spastin/Vps4, C-terminal |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q503S1 | InterPro | 736 | ||||||
| UniProtKB:B2GQM4 | InterPro | 736 | ||||||
| UniProtKB:A0A8M9QFE1 | InterPro | 747 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available