ZFIN is now using GRCz12tu for Genomic Data
Gene
fign
- ID
- ZDB-GENE-050522-339
- Name
- fidgetin
- Symbol
- fign Nomenclature History
- Previous Names
-
- zgc:110229
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATP hydrolysis activity and microtubule severing ATPase activity. Predicted to be involved in microtubule severing. Predicted to be located in centrosome; microtubule; and nuclear matrix. Predicted to be active in cytoplasm and nucleus. Is expressed in lens placode; nervous system; solid lens vesicle; and somite. Orthologous to human FIGN (fidgetin, microtubule severing factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110229 (18 images)
- eu950 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR015415 | Spastin/Vps4, C-terminal |
| Domain | IPR047828 | Fidgetin, ATPase domain |
| Family | IPR050304 | Microtubule-severing AAA ATPase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | ATPase, AAA-type, core | Fidgetin, ATPase domain | Microtubule-severing AAA ATPase | P-loop containing nucleoside triphosphate hydrolase | Spastin/Vps4, C-terminal |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q503S1 | InterPro | 736 | ||||||
| UniProtKB:B2GQM4 | InterPro | 736 | ||||||
| UniProtKB:A0A8M9QFE1 | InterPro | 747 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers