Gene
alox5b.3
- ID
- ZDB-GENE-050522-330
- Name
- arachidonate 5-lipoxygenase b, tandem duplicate 3
- Symbol
- alox5b.3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable arachidonate 5-lipoxygenase activity. Predicted to be involved in linoleic acid metabolic process and lipid oxidation. Predicted to be located in cytoplasm. Predicted to be active in nuclear envelope. Is expressed in EVL and periderm. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma (multiple); pancreatic cancer; and pulmonary tuberculosis. Orthologous to human ALOX5 (arachidonate 5-lipoxygenase).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb171 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Binding_site | IPR020833 | Lipoxygenase, iron binding site |
Conserved_site | IPR020834 | Lipoxygenase, conserved site |
Domain | IPR001024 | PLAT/LH2 domain |
Domain | IPR013819 | Lipoxygenase, C-terminal |
Family | IPR000907 | Lipoxygenase |
Family | IPR001885 | Lipoxygenase, mammalian |
Homologous_superfamily | IPR036226 | Lipoxigenase, C-terminal domain superfamily |
Homologous_superfamily | IPR036392 | PLAT/LH2 domain superfamily |
Domain Details Per Protein
Protein | Length | Lipoxigenase, C-terminal domain superfamily | Lipoxygenase | Lipoxygenase, conserved site | Lipoxygenase, C-terminal | Lipoxygenase, iron binding site | Lipoxygenase, mammalian | PLAT/LH2 domain | PLAT/LH2 domain superfamily |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1R442
|
676 | ||||||||
UniProtKB:Q503R7
|
676 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
alox5b.3-201
(1)
|
Ensembl | 2,576 nt | ||
mRNA |
alox5b.3-204
(1)
|
Ensembl | 4,090 nt | ||
ncRNA |
alox5b.3-002
(1)
|
Ensembl | 434 nt | ||
ncRNA |
alox5b.3-003
(1)
|
Ensembl | 962 nt |
Interactions and Pathways
No data available
Plasmids
No data available