Gene
nle1
- ID
- ZDB-GENE-050522-321
- Name
- notchless homolog 1 (Drosophila)
- Symbol
- nle1 Nomenclature History
- Previous Names
-
- fc12b09
- fc45f01
- wu:fc12b09
- wu:fc45f01
- zgc:110281 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to be involved in Notch signaling pathway and ribosomal large subunit assembly. Predicted to be located in nucleus. Predicted to be active in nucleolus. Is expressed in alar plate midbrain region; nervous system; optic vesicle; and pharyngeal arch. Orthologous to human NLE1 (notchless homolog 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110281 (1 image)
- IMAGE:7155292 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR001632 | G-protein, beta subunit |
| Domain | IPR012972 | NLE |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein, beta subunit | G-protein beta WD-40 repeat | NLE | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QDT3
|
476 |
Interactions and Pathways
No data available
Plasmids
No data available