ZFIN is now using GRCz12tu for Genomic Data
Gene
nle1
- ID
- ZDB-GENE-050522-321
- Name
- notchless homolog 1 (Drosophila)
- Symbol
- nle1 Nomenclature History
- Previous Names
-
- fc12b09
- fc45f01
- wu:fc12b09
- wu:fc45f01
- zgc:110281 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in regulation of Notch signaling pathway. Predicted to act upstream of or within Notch signaling pathway. Predicted to be located in nucleus. Predicted to be active in nucleolus. Is expressed in alar plate midbrain region; nervous system; optic vesicle; and pharyngeal arch. Orthologous to human NLE1 (notchless homolog 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110281 (1 image)
- IMAGE:7155292 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR001632 | G-protein, beta subunit |
| Domain | IPR012972 | NLE |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | G-protein, beta subunit | G-protein beta WD-40 repeat | NLE | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QDT3 | InterPro | 476 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers