Gene

cfap52

ID

ZDB-GENE-050522-296

Name

cilia and flagella associated protein 52

Symbol

cfap52 Nomenclature History

Previous Names

fj15f10
si:dkey-28k21.1
wdr16
wu:fj15f10
zgc:111988 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to be located in axoneme and motile cilium. Is expressed in nervous system and pronephros. Human ortholog(s) of this gene implicated in visceral heterotaxy 10. Orthologous to human CFAP52 (cilia and flagella associated protein 52).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Hirschner et al., 2007

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cfap52 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
visceral heterotaxy 10	Alliance	Heterotaxy, visceral, 10, autosomal, with male infertility	619607

Associated With cfap52 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Family	IPR050630	WD repeat Echinoderm Microtubule-associated Protein-like
Homologous_superfamily	IPR011047	Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat