Gene
edc3
- ID
- ZDB-GENE-050522-287
- Name
- enhancer of mRNA decapping 3 homolog (S. cerevisiae)
- Symbol
- edc3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have mRNA binding activity and phosphodiesterase decapping endonuclease activity. Predicted to be involved in cytoplasmic mRNA processing body assembly and deadenylation-independent decapping of nuclear-transcribed mRNA. Predicted to localize to P-body. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human EDC3 (enhancer of mRNA decapping 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151288 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 50 | Alliance | ?Intellectual developmental disorder, autosomal recessive 50 | 616460 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DFDF domain | FDF domain | Lsm14-like, N-terminal | Lsm16, N-terminal | Sm domain | YjeF N-terminal domain | YjeF N-terminal domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QL27
|
506 | |||||||
|
UniProtKB:Q502M5
|
507 | |||||||
|
UniProtKB:A0A8M2BAE2
|
486 | |||||||
|
UniProtKB:A0A8M2BA31
|
484 |
Interactions and Pathways
No data available
Plasmids
No data available