Gene
letm1
- ID
- ZDB-GENE-050522-154
- Name
- leucine zipper-EF-hand containing transmembrane protein 1
- Symbol
- letm1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have calcium:proton antiporter activity. Predicted to be involved in cellular calcium ion homeostasis and protein complex oligomerization. Predicted to localize to mitochondrial inner membrane. Orthologous to human LETM1 (leucine zipper and EF-hand containing transmembrane protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109969 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodegeneration, childhood-onset, with multisystem involvement due to mitochondrial dysfunction | 620089 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | LETM1-like, ribosome-binding domain | LETM1/MDM38-like |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B3G3
|
774 | |||||
|
UniProtKB:A0A8M3BEI6
|
779 | |||||
|
UniProtKB:A0A8M3AYY0
|
785 | |||||
|
UniProtKB:A0A8M3AYW7
|
768 | |||||
|
UniProtKB:Q1LY46
|
757 |
Interactions and Pathways
No data available
Plasmids
No data available