Gene
tp53rk
- ID
- ZDB-GENE-050522-123
- Name
- TP53 regulating kinase
- Symbol
- tp53rk Nomenclature History
- Previous Names
-
- fd05d02
- wu:fd05d02
- zgc:110000 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and tRNA threonylcarbamoyladenosine metabolic process. Predicted to act upstream of or within phosphorylation and tRNA processing. Predicted to be part of EKC/KEOPS complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Orthologous to human TP53RK (TP53 regulating kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907866 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Galloway-Mowat syndrome 4 | Alliance | Galloway-Mowat syndrome 4 | 617730 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase Bud32 | Tyrosine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:F1QB90
|
231 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tp53rk-201
(1)
|
Ensembl | 5,295 nt |
Interactions and Pathways
No data available
Plasmids
No data available