Gene

ptprz1b

ID

ZDB-GENE-050506-100

Name

protein tyrosine phosphatase receptor type Z1b

Symbol

ptprz1b Nomenclature History

Previous Names

fc63b11
im:6906068
si:ch211-258f14.6 (1)
wu:fc63b11

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in peptidyl-tyrosine dephosphorylation. Predicted to localize to integral component of membrane. Is expressed in central nervous system; cranial ganglion; neural rod; and neural tube. Orthologous to human PTPRZ1 (protein tyrosine phosphatase receptor type Z1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6906068 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from Katraki-Pavlou et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptprz1b Human Ortholog

No data available

Associated With ptprz1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR001148	Alpha carbonic anhydrase domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR003961	Fibronectin type III
Domain	IPR041887	Receptor-type tyrosine-protein phosphatase, carbonic anhydrase domain
Family	IPR050348	Protein-Tyrosine Phosphatase
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036398	Alpha carbonic anhydrase domain superfamily

Domain Details Per Protein

Protein	Length	Alpha carbonic anhydrase domain	Alpha carbonic anhydrase domain superfamily	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin-like fold	Protein-Tyrosine Phosphatase	Protein-tyrosine phosphatase, active site	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Receptor-type tyrosine-protein phosphatase, carbonic anhydrase domain	Tyrosine-specific protein phosphatase, PTPase domain	Tyrosine-specific protein phosphatases domain
UniProtKB:A0A8M9PI59 InterPro	1291
UniProtKB:B8A5J4 InterPro	1298
UniProtKB:A0A8M3B8R4 InterPro	1457
UniProtKB:A0A8M9Q6N2 InterPro	1450

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptprz1b-201 (1) Ensembl	Ensembl	1,535 nt	Select Tool
mRNA	ptprz1b-202 (1) Ensembl	Ensembl	4,365 nt	Select Tool
mRNA	ptprz1b-203 (1) Ensembl	Ensembl	704 nt	Select Tool
mRNA	ptprz1b-205 (1) Ensembl	Ensembl	3,912 nt	Select Tool ZFIN BLAST
ncRNA	ptprz1b-004 (1) Ensembl	Ensembl	599 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations