Gene
hmgb3a
- ID
- ZDB-GENE-050428-1
- Name
- high mobility group box 3a
- Symbol
- hmgb3a Nomenclature History
- Previous Names
-
- wu:fb17a03
- wu:fk52f12
- zgc:162415
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin. Is expressed in several structures, including axis; intermediate cell mass of mesoderm; mesoderm; nervous system; and pectoral fin bud. Human ortholog(s) of this gene implicated in syndromic microphthalmia 13. Orthologous to human HMGB3 (high mobility group box 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7156270 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
?Microphthalmia, syndromic 13 | 300915 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | High mobility group box domain | High mobility group box domain superfamily |
---|---|---|---|
UniProtKB:F1QGP8
|
213 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
aberrant processed transcript |
hmgb3a-201
(1)
|
Havana | 589 nt | |
mRNA |
hmgb3a-202
(1)
|
Havana | 1709 nt | |
mRNA |
hmgb3a-204
(1)
|
Havana | 837 nt | |
ncRNA |
hmgb3a-002
(1)
|
Havana | 675 nt |
Interactions and Pathways
No data available
Plasmids
No data available