Gene

ddb2

ID
ZDB-GENE-050419-169
Name
damage-specific DNA binding protein 2
Symbol
ddb2 Nomenclature History
Previous Names
  • si:dkey-45f10.3
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to contribute to damaged DNA binding activity. Predicted to be involved in DNA repair and response to UV. Predicted to localize to nucleus. Is expressed in central nervous system and neurons. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group E. Orthologous to human DDB2 (damage specific DNA binding protein 2).
Genome Resources
Note
None
Expression
All Expression Data
11 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ddb2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
xeroderma pigmentosum group E Alliance Xeroderma pigmentosum, group E, DDB-negative subtype 278740
Associated With ddb2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR017986 WD40-repeat-containing domain
Family IPR033312 DNA damage-binding protein 2
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length DNA damage-binding protein 2 WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Z4YI04 497
UniProtKB:A0A2R8PYM3 496
UniProtKB:Q2YDS1 496
UniProtKB:Z4YIW2 490
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations