Gene

chtf8

ID

ZDB-GENE-050419-148

Name

CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)

Symbol

chtf8 Nomenclature History

Previous Names

si:ch211-218c6.5 (1)
zgc:158641

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable DNA binding activity. Predicted to act upstream of or within DNA replication and mitotic sister chromatid cohesion. Predicted to be located in nucleus. Predicted to be part of Ctf18 RFC-like complex. Orthologous to human CHTF8 (chromosome transmission fidelity factor 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

No data available

Sequence Targeting Reagents

No data available

Human Disease

Associated With chtf8 Human Ortholog

No data available

Associated With chtf8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR018607	Chromosome transmission fidelity protein 8

Domain Details Per Protein

Protein	Additional Resources	Length	Chromosome transmission fidelity protein 8
UniProtKB:Q1LUE7	InterPro	124

Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 18

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	chtf8-201 (1) Ensembl	Ensembl		1,474 nt	Select Tool ZFIN BLAST
mRNA	chtf8-202 (1) Ensembl	Ensembl		908 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	CH211-218C6	BX950194	ZFIN Curated Data
Encodes	cDNA	MGC:158641	BC133141	ZFIN Curated Data
Encodes	cDNA	MGC:198368	BC171641	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001044336 (1)	1330 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX323598 (1)	197329 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q1LUE7 (1)	124 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	CHTF8	16	Ensembl:ENSG00000168802 Gene:54921 HGNC:24353 OMIM:613202	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Chtf8	8	Ensembl:ENSMUSG00000046691 Gene:214987 MGI:2443370	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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