Gene
dph1
- ID
- ZDB-GENE-050417-411
- Name
- diphthamide biosynthesis 1
- Symbol
- dph1 Nomenclature History
- Previous Names
-
- zgc:110702 (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have transferase activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Predicted to localize to cytoplasm and nucleus. Orthologous to human DPH1 (diphthamide biosynthesis 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| diphthamide deficiency syndrome 1 | Alliance | Developmental delay with short stature, dysmorphic facial features, and sparse hair | 616901 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Diphthamide synthesis DPH1/DPH2 | Diphthamide synthesis DPH1/DPH2, domain 1 | Diphthamide synthesis DPH1/DPH2, domain 2 | Diphthamide synthesis DPH1/DPH2, domain 3 |
|---|---|---|---|---|---|
|
UniProtKB:Q567W6
|
381 | ||||
|
UniProtKB:A0A8M2B3R1
|
439 | ||||
|
UniProtKB:A0A8M2B3R3
|
438 |
Interactions and Pathways
No data available
Plasmids
No data available