Gene
ppp3cb
- ID
- ZDB-GENE-050417-406
- Name
- protein phosphatase 3, catalytic subunit, beta isozyme
- Symbol
- ppp3cb Nomenclature History
- Previous Names
-
- wu:fq19c08
- zgc:110141
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have calmodulin binding activity and calmodulin-dependent protein phosphatase activity. Predicted to be involved in calcineurin-NFAT signaling cascade. Predicted to localize to calcineurin complex and cytosol. Human ortholog(s) of this gene implicated in infantile or early childhood epileptic encephalopathy 1. Is expressed in hatching gland; integument; nervous system; and pharyngeal arch. Orthologous to human PPP3CA (protein phosphatase 3 catalytic subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 21 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110141 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR004843 | Calcineurin-like phosphoesterase domain, ApaH type |
Domain | IPR006186 | Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase |
Domain | IPR041751 | PP2B, metallophosphatase domain |
Family | IPR043360 | PP2B |
Homologous_superfamily | IPR029052 | Metallo-dependent phosphatase-like |
Domain Details Per Protein
Protein | Length | Calcineurin-like phosphoesterase domain, ApaH type | Metallo-dependent phosphatase-like | PP2B | PP2B, metallophosphatase domain | Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase |
---|---|---|---|---|---|---|
UniProtKB:A0A8M9QGE2
|
510 | |||||
UniProtKB:Q568R4
|
511 | |||||
UniProtKB:A0A8M3AZJ8
|
506 | |||||
UniProtKB:A0A8M3BEY4
|
522 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
ppp3cb-201
(1)
|
Ensembl | 3,158 nt | ||
mRNA |
ppp3cb-202
(1)
|
Ensembl | 992 nt |
Interactions and Pathways
No data available
Plasmids
No data available