Gene
stmn1b
- ID
- ZDB-GENE-050417-397
- Name
- stathmin 1b
- Symbol
- stmn1b Nomenclature History
- Previous Names
-
- fj38b07
- fj43c10
- stathmin 1/oncoprotein 18b (1)
- wu:fj38b07
- wu:fj43c10
- zgc:110159
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable tubulin binding activity. Predicted to be involved in microtubule depolymerization; neuron projection development; and regulation of microtubule polymerization or depolymerization. Predicted to be located in microtubule. Predicted to be active in cytoplasm and neuron projection. Is expressed in nervous system; neural crest; neural tube; and trigeminal placode. Orthologous to human STMN1 (stathmin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6892170 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-stmn1b | N/A | Carretero-Rodriguez et al., 2021 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Stathmin, conserved site | Stathmin family | Stathmin superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q568Q7 | InterPro | 149 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stmn1b-201
(1)
|
Ensembl | 1,687 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-255I3 | ZFIN Curated Data | |
| Encodes | EST | cegs2589 | Rauch et al., 2003 | |
| Encodes | EST | fj38b07 | ||
| Encodes | EST | fj43c10 | ||
| Encodes | EST | IMAGE:6892170 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:110159 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001017850 (1) | 1726 nt | ||
| Genomic | GenBank:CR626886 (1) | 165396 nt | ||
| Polypeptide | UniProtKB:Q568Q7 (1) | 149 aa |
- Jing, Y., Luo, Y., Li, L., Liu, M., Liu, J.X. (2024) Deficiency of copper responsive gene stmn4 induces retinal developmental defects. Cell biology and toxicology. 40:22
- Carretero-Rodriguez, L., Guðjónsdóttir, R., Poparic, I., Reilly, M.L., Chol, M., Bianco, I.H., Chiapello, M., Feret, R., Deery, M.J., Guthrie, S. (2021) The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system. The Journal of neuroscience : the official journal of the Society for Neuroscience. 41(31):6652-6672
- Metikala, S., Casie Chetty, S., Sumanas, S. (2021) Single-cell transcriptome analysis of the zebrafish embryonic trunk. PLoS One. 16:e0254024
- Zhang, X.Y., Liu, Y.H., Liu, D.Z., Xu, J.Y., Zhang, Q. (2021) Insulin-Mimic Components in Acer truncatum Leaves: Bio-Guided Isolation, Annual Variance Profiling and Regulating Pathway Investigated by Omics. Pharmaceuticals (Basel, Switzerland). 14(7):
- Hou, Y., Lee, H.J., Chen, Y., Ge, J., Osman, F.O.I., McAdow, A.R., Mokalled, M.H., Johnson, S.L., Zhao, G., Wang, T. (2020) Cellular diversity of the regenerating caudal fin. Science advances. 6:eaba2084
- Lange, C., Rost, F., Machate, A., Reinhardt, S., Lesche, M., Weber, A., Kuscha, V., Dahl, A., Rulands, S., Brand, M. (2020) Single cell sequencing of radial glia progeny reveals diversity of newborn neurons in the adult zebrafish brain. Development (Cambridge, England). 147(1):
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Cardoso, J.C., Bergqvist, C.A., Felix, R.C., Larhammar, D. (2016) Corticotropin-releasing hormone family evolution: five ancestral genes remain in some lineages. Journal of molecular endocrinology. 57(1):73-86
- Lin, M.J., Lee, S.J. (2016) Stathmin-like 4 is critical for the maintenance of neural progenitor cells in dorsal midbrain of zebrafish larvae. Scientific Reports. 6:36188
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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