Gene
tmco1
- ID
- ZDB-GENE-050417-344
- Name
- transmembrane and coiled-coil domains 1
- Symbol
- tmco1 Nomenclature History
- Previous Names
-
- sb:cb729
- zgc:110322
- zgc:92740
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have calcium channel activity. Involved in calcium ion transmembrane transport and endoplasmic reticulum calcium ion homeostasis. Localizes to endoplasmic reticulum. Is expressed in several structures, including axis; hatching gland; lens; polster; and solid lens vesicle. Orthologous to human TMCO1 (transmembrane and coiled-coil domains 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb729 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 1 | Alliance | Craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development 1 | 213980 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calcium load-activated calcium channel | Integral membrane protein EMC3/TMCO1-like |
|---|---|---|---|
|
UniProtKB:Q6DGW9
|
188 |
Interactions and Pathways
No data available
Plasmids
No data available