Gene

bdh2

ID
ZDB-GENE-050417-343
Name
3-hydroxybutyrate dehydrogenase, type 2
Symbol
bdh2 Nomenclature History
Previous Names
  • zgc:110323
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have 3-hydroxybutyrate dehydrogenase activity and oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Involved in erythrocyte maturation; heme metabolic process; and hemoglobin biosynthetic process. Predicted to localize to cytoplasm. Orthologous to human BDH2 (3-hydroxybutyrate dehydrogenase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Devireddy et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bdh2 Human Ortholog
No data available
Associated With bdh2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020904 Short-chain dehydrogenase/reductase, conserved site
Family IPR002347 Short-chain dehydrogenase/reductase SDR
Family IPR051122 Short-chain dehydrogenase/reductase superfamily enzyme
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase, conserved site Short-chain dehydrogenase/reductase SDR Short-chain dehydrogenase/reductase superfamily enzyme
UniProtKB:Q561X9 245
UniProtKB:B2GSA5 245
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA bdh2-201 (1) Ensembl 1,061 nt
mRNA bdh2-202 (1) Ensembl 1,016 nt
mRNA bdh2-203 (1) Ensembl 854 nt
mRNA bdh2-207 (1) Ensembl 741 nt
ncRNA bdh2-004 (1) Ensembl 534 nt
ncRNA bdh2-005 (1) Ensembl 787 nt
ncRNA bdh2-006 (1) Ensembl 492 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations