Gene

ndufs3

ID

ZDB-GENE-050417-274

Name

NADH:ubiquinone oxidoreductase core subunit S3

Symbol

ndufs3 Nomenclature History

Previous Names

zgc:112520

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Is expressed in male organism. Orthologous to human NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7148616 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ndufs3 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
nuclear type mitochondrial complex I deficiency 8	Alliance	Mitochondrial complex I deficiency, nuclear type 8	618230

Associated With ndufs3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020396	NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site
Domain	IPR001268	NADH:ubiquinone oxidoreductase, 30kDa subunit
Family	IPR010218	NADH dehydrogenase, subunit C
Homologous_superfamily	IPR037232	NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily