Gene

mppe1

ID

ZDB-GENE-050417-195

Name

metallophosphoesterase 1

Symbol

mppe1 Nomenclature History

Previous Names

zgc:112219 (1)

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to enable GPI anchor binding activity; GPI-mannose ethanolamine phosphate phosphodiesterase activity; and manganese ion binding activity. Predicted to be involved in GPI anchor biosynthetic process and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be located in cis-Golgi network; endoplasmic reticulum exit site; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human MPPE1 (metallophosphoesterase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:112219 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mppe1 Human Ortholog

No data available

Associated With mppe1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004843	Calcineurin-like phosphoesterase domain, ApaH type
Domain	IPR039541	Metallophosphoesterase 1, metallophosphatase domain
Family	IPR033308	PGAP5/Cdc1/Ted1
Homologous_superfamily	IPR029052	Metallo-dependent phosphatase-like