Gene
mrpl12
- ID
- ZDB-GENE-050417-187
- Name
- mitochondrial ribosomal protein L12
- Symbol
- mrpl12 Nomenclature History
- Previous Names
-
- im:6893415
- zgc:112445
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; optic vesicle; and pectoral fin. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 45. Orthologous to human MRPL12 (mitochondrial ribosomal protein L12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6893415 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 45 | Alliance | ?Combined oxidative phosphorylation deficiency 45 | 618951 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR008932 | Large ribosomal subunit protein bL12, oligomerization |
| Domain | IPR013823 | Large ribosomal subunit protein bL12, C-terminal |
| Family | IPR000206 | Large ribosomal subunit protein bL12 |
| Homologous_superfamily | IPR014719 | Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like |
| Homologous_superfamily | IPR036235 | Large ribosomal subunit protein bL12, oligomerization domain superfamily |
Domain Details Per Protein
| Protein | Length | Large ribosomal subunit protein bL12 | Large ribosomal subunit protein bL12, C-terminal | Large ribosomal subunit protein bL12, oligomerization | Large ribosomal subunit protein bL12, oligomerization domain superfamily | Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like |
|---|---|---|---|---|---|---|
|
UniProtKB:Q566V8
|
194 | |||||
|
UniProtKB:X1WHQ5
|
199 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mrpl12-201
(1)
|
Ensembl | 1,057 nt | ||
| mRNA |
mrpl12-202
(1)
|
Ensembl | 1,287 nt |
Interactions and Pathways
No data available
Plasmids
No data available