Gene

stard4

ID

ZDB-GENE-050417-168

Name

StAR related lipid transfer domain containing 4

Symbol

stard4 Nomenclature History

Previous Names

zgc:112466

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable cholesterol binding activity and cholesterol transfer activity. Predicted to be involved in cholesterol import; cholesterol transport involved in cholesterol storage; and intracellular cholesterol transport. Predicted to be active in cytosol and endoplasmic reticulum. Orthologous to human STARD4 (StAR related lipid transfer domain containing 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

No data available

Sequence Targeting Reagents

No data available

Human Disease

Associated With stard4 Human Ortholog

No data available

Associated With stard4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002913	START domain
Family	IPR042555	StAR-related lipid transfer protein 4
Homologous_superfamily	IPR023393	START-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PTU1	InterPro	204
UniProtKB:A0A8M6YUG2	InterPro	164
UniProtKB:Q566U7	InterPro	198
UniProtKB:A0A8M2BHK6	InterPro	221

Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 21

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	stard4-201 (1) Ensembl	Ensembl	1,223 nt	Select Tool ZFIN BLAST
ncRNA	stard4-002 (1) Ensembl	Ensembl	934 nt	Select Tool ZFIN BLAST
ncRNA	stard4-003 (1) Ensembl	Ensembl	470 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	Fosmid	ZFOS-1462C8	CU694470	ZFIN Curated Data
Encodes	cDNA	MGC:112466	BC093326	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001017679 (1)	1201 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CU694470 (1)	41108 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A8M2BHK6 (1)	221 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	STARD4	5	Ensembl:ENSG00000164211 Gene:134429 HGNC:18058 OMIM:607049	Amino acid sequence comparison (1)
Mouse	Stard4	18	Ensembl:ENSMUSG00000024378 Gene:170459 MGI:2156764	Amino acid sequence comparison (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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