Gene

nsdhl

ID
ZDB-GENE-050417-163
Name
NAD(P) dependent steroid dehydrogenase-like
Symbol
nsdhl Nomenclature History
Previous Names
  • zgc:112474 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Acts upstream of or within response to yeast. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in CHILD syndrome and CK syndrome. Orthologous to human NSDHL (NAD(P) dependent steroid dehydrogenase-like).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Weger et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nsdhl Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
CHILD syndrome Alliance CHILD syndrome 308050
CK syndrome Alliance CK syndrome 300831
Associated With nsdhl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 3-beta hydroxysteroid dehydrogenase/isomerase NAD(P)-binding domain superfamily
UniProtKB:Q566U2 345
UniProtKB:A0A0J9YJF2 184
UniProtKB:A0A0R4IYR2 345
UniProtKB:A0A0J9YJ53 200
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations