Gene

mrto4

ID

ZDB-GENE-050417-142

Name

MRT4 homolog, ribosome maturation factor

Symbol

mrto4 Nomenclature History

Previous Names

fb71a02
wu:fb71a02
zgc:110388

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to be involved in nuclear-transcribed mRNA catabolic process; rRNA processing; and ribosomal large subunit biogenesis. Predicted to act upstream of or within ribosomal large subunit assembly. Predicted to be located in cytoplasm and nucleus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Orthologous to human MRTO4 (MRT4 homolog, ribosome maturation factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Zhou et al., 2020

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mrto4 Human Ortholog

No data available

Associated With mrto4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040637	Large ribosomal subunit protein uL10-like, insertion domain
Family	IPR001790	Large ribosomal subunit protein uL10
Family	IPR033867	Ribosome assembly factor Mrt4
Family	IPR051742	Ribosomal Assembly Factor uL10
Homologous_superfamily	IPR043141	Large ribosomal subunit protein uL10-like domain superfamily
Homologous_superfamily	IPR043164	Large ribosomal subunit protein uL10-like, insertion domain superfamily

Domain Details Per Protein

Protein	Length	Large ribosomal subunit protein uL10	Large ribosomal subunit protein uL10-like domain superfamily	Large ribosomal subunit protein uL10-like, insertion domain	Large ribosomal subunit protein uL10-like, insertion domain superfamily	Ribosomal Assembly Factor uL10	Ribosome assembly factor Mrt4
UniProtKB:Q568C9 InterPro	242

Transcripts

Genome Browsers

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	mrto4-201 (1) Ensembl	Ensembl		1,068 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations