Gene

abcb8

ID

ZDB-GENE-050410-6

Name

ATP-binding cassette, sub-family B (MDR/TAP), member 8

Symbol

abcb8 Nomenclature History

Previous Names

zgc:113037

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to enable ATP binding activity and ATPase-coupled transmembrane transporter activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial ATP-gated potassium channel complex. Predicted to be active in membrane. Is expressed in female organism. Orthologous to human ABCB8 (ATP binding cassette subfamily B member 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:113037 (1 image)
IMAGE:7155111 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcb8 Human Ortholog

No data available

Associated With abcb8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR011527	ABC transporter type 1, transmembrane domain
Family	IPR039421	Type 1 protein exporter
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036640	ABC transporter type 1, transmembrane domain superfamily