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ZIRC
ZFIN ID: ZDB-GENE-050327-68
Gene Name: inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Gene Symbol: ikbkg
Sequence Ontology ID : SO:0000704

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Previous Names: ikky (1), fj33c07, nemo (1), wu:fj33c07, zgc:113492

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have K63-linked polyubiquitin modification-dependent protein binding activity. Involved in I-kappaB phosphorylation and positive regulation of I-kappaB kinase/NF-kappaB signaling.  ...
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (2 images) from Thisse et al., 2004 [IMAGE:7147563]
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
c220Gt Transgenic Insertion Unknown Unknown DNA
s838 Unknown Unknown Unknown ENU
sa24293 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29899 Point Mutation Unknown Premature Stop ENU
    sa44998 Point Mutation Unknown Unknown ENU
    PHENOTYPE
    Data: Fig. S2 from Davison et al., 2007
    Observed in:
    DISEASE ASSOCIATED WITH ikbkg HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Bloch-Sulzberger syndrome Incontinentia pigmenti 308300
    hypohidrotic ectodermal dysplasia Ectodermal dysplasia and immunodeficiency 1 300291
    Immunodeficiency 33 300636
    Invasive pneumococcal disease, recurrent isolated, 2 300640
    Immunodeficiency, isolated 300584
    Ectodermal, dysplasia, anhidrotic, lymphedema and immunodeficiency 300301
    DISEASE ASSOCIATED WITH ikbkg VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process I-kappaB phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein binding (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA ikbkg-003 (1) 830
    mRNA ikbkg-201 (1) 2448
    ikbkg-202 (1) 2054
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ikbkg No data available
    MARKER RELATIONSHIPS
    ikbkgContained in: [BAC] CH211-272P8 (1) (order this), DKEY-95F11 (1) (order this)
    ikbkgEncodes: [EST] fj33c07, IMAGE:7147563 (1) (order this)
    [cDNA] MGC:113492 (1) (order this), MGC:193114 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001014344 (1) 2480bp
    Genomic GenBank:CR354375 (1) 133570bp
    Select Tool
    Polypeptide UniProtKB:F1QHG7 (1) 602aa
    Sequence Clusters UniGene:69759 (1)
    Sequence Information (all 27)
    ORTHOLOGY for ikbkg (Chr: 23)
    CITATIONS (29)