Gene
slc47a1
- ID
- ZDB-GENE-050327-20
- Name
- solute carrier family 47 member 1
- Symbol
- slc47a1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable transmembrane transporter activity. Predicted to act upstream of or within xenobiotic detoxification by transmembrane export across the plasma membrane. Predicted to be active in membrane. Is expressed in brain; eye; liver; pleuroperitoneal region; and yolk syncytial layer. Orthologous to several human genes including SLC47A1 (solute carrier family 47 member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7154749 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Multi antimicrobial extrusion protein | Multidrug and toxic compound extrusion family, eukaryotic |
|---|---|---|---|---|
| UniProtKB:A0A8F5XXW9 | InterPro | |||
| UniProtKB:A1L2E7 | InterPro | 629 | ||
| UniProtKB:A0A8M9PCM0 | InterPro | 656 | ||
| UniProtKB:A0A8M1N4Q5 | InterPro | 629 | ||
| UniProtKB:A0AB32TBQ0 | InterPro | 634 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc47a1-201
(1)
|
Ensembl | 2,456 nt | ||
| mRNA |
slc47a1-202
(1)
|
Ensembl | 899 nt | ||
| mRNA |
slc47a1-203
(1)
|
Ensembl | 903 nt | ||
| mRNA |
slc47a1-204
(1)
|
Ensembl | 1,650 nt | ||
| mRNA |
slc47a1-205
(1)
|
Ensembl | 5,007 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-221P4 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7154749 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:113362 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:158848 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:191366 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192945 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001014310 (1) | 2430 nt | ||
| Genomic | GenBank:BX248108 (1) | 230610 nt | ||
| Polypeptide | UniProtKB:A0A8M9PCM0 (1) | 656 aa |
- Lončar, J., Popović, M., Krznar, P., Zaja, R., Smital, T. (2016) The first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio). Scientific Reports. 6:28937
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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