Gene

plcxd3

ID

ZDB-GENE-050327-10

Name

phosphatidylinositol-specific phospholipase C, X domain containing 3

Symbol

plcxd3 Nomenclature History

Previous Names

fc10h08
wu:cegs2770
wu:fc10h08
wu:fq34d10
zgc:110845

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to enable phosphoric diester hydrolase activity. Predicted to act upstream of or within lipid catabolic process and signal transduction. Predicted to be active in synapse. Is expressed in basal plate midbrain region; central nervous system; neurons; otic vesicle; and pharyngeal arch. Orthologous to human PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7155724 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With plcxd3 Human Ortholog

No data available

Associated With plcxd3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000909	Phosphatidylinositol-specific phospholipase C, X domain
Family	IPR042158	PI-PLC X domain-containing protein 1/2/3
Family	IPR051057	Phosphoinositide phospholipase C domain-containing protein
Homologous_superfamily	IPR017946	PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily