Gene
ndufc2
- ID
- ZDB-GENE-050320-87
- Name
- NADH:ubiquinone oxidoreductase subunit C2
- Symbol
- ndufc2 Nomenclature History
- Previous Names
-
- zgc:110155
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to act upstream of or within mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to several human genes including NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6903339 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Mitochondrial complex I deficiency, nuclear type 36 | 619170 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR009423 | NADH dehydrogenase [ubiquinone] 1 subunit C2, NDUC2 |
Domain Details Per Protein
| Protein | Length | NADH dehydrogenase [ubiquinone] 1 subunit C2, NDUC2 |
|---|---|---|
|
UniProtKB:Q5BJK4
|
110 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufc2-201
(1)
|
Ensembl | 538 nt |
Interactions and Pathways
No data available
Plasmids
No data available