Gene

aoc2

ID

ZDB-GENE-050320-133

Name

amine oxidase copper containing 2

Symbol

aoc2 Nomenclature History

Previous Names

fa94a08
fe14c05
wu:fa94a08
wu:fe14c05
zgc:113006

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to enable copper ion binding activity and primary methylamine oxidase activity. Predicted to be involved in amine metabolic process. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human AOC2 (amine oxidase copper containing 2) and AOC3 (amine oxidase copper containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With aoc2 Human Ortholog

No data available

Associated With aoc2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR049947	Copper amine oxidase, copper-binding site
Domain	IPR015798	Copper amine oxidase, catalytic domain
Domain	IPR015800	Copper amine oxidase, N2-terminal
Domain	IPR015802	Copper amine oxidase, N3-terminal
Family	IPR000269	Copper amine oxidase
Homologous_superfamily	IPR016182	Copper amine oxidase, N-terminal
Homologous_superfamily	IPR036460	Copper amine oxidase, catalytic domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Copper amine oxidase	Copper amine oxidase, catalytic domain	Copper amine oxidase, catalytic domain superfamily	Copper amine oxidase, copper-binding site	Copper amine oxidase, N2-terminal	Copper amine oxidase, N3-terminal	Copper amine oxidase, N-terminal
UniProtKB:A0A8M1N4I9	InterPro	754

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	aoc2-202 (1) Ensembl	Ensembl	1,513 nt	Select Tool ZFIN BLAST
mRNA	aoc2-203 (1) Ensembl	Ensembl	2,665 nt	Select Tool ZFIN BLAST
mRNA	aoc2-204 (1) Ensembl	Ensembl	673 nt	Select Tool ZFIN BLAST
ncRNA	aoc2-003 (1) Ensembl	Ensembl	866 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations