Gene
pgap2
- ID
- ZDB-GENE-050320-119
- Name
- post-GPI attachment to proteins 2
- Symbol
- pgap2 Nomenclature History
- Previous Names
-
- frag1
- wu:fc51g11
- zgc:101568 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 3. Orthologous to human PGAP2 (post-GPI attachment to proteins 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101568 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hyperphosphatasia with impaired intellectual development syndrome 3 | Alliance | Hyperphosphatasia with impaired intellectual development syndrome 3 | 614207 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Frag1/DRAM/Sfk1 | Post-GPI attachment to proteins factor 2 |
|---|---|---|---|
|
UniProtKB:Q5BL33
|
231 | ||
|
UniProtKB:G1K2N7
|
254 |
Interactions and Pathways
No data available
Plasmids
No data available