Gene

lgals2a

ID
ZDB-GENE-050318-2
Name
lectin, galactoside-binding, soluble, 2a
Symbol
lgals2a Nomenclature History
Previous Names
  • Drgal1-L2 (1)
  • lgals1l2
  • zgc:86752
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits galactoside binding activity and laminin binding activity. Involved in several processes, including positive regulation of wound healing; skeletal muscle fiber development; and sprouting angiogenesis. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in myocardial infarction. Is expressed in digestive system; musculature system; nervous system; notochord; and spleen. Orthologous to human LGALS2 (galectin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Ahmed et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lgals2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Myocardial infarction, susceptibility to} 608446
Associated With lgals2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001079 Galectin, carbohydrate recognition domain
Family IPR044156 Galectin-like
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily Galectin, carbohydrate recognition domain Galectin-like
UniProtKB:Q6IQI2 134
UniProtKB:Q6TGN5 134
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lgals2a-201 (1) Ensembl 2,061 nt
mRNA lgals2a-202 (1) Ensembl 883 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations