Gene
ntn4
- ID
- ZDB-GENE-050310-1
- Name
- netrin 4
- Symbol
- ntn4 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Involved in vasculature development. Acts upstream of or within blood vessel morphogenesis. Predicted to be located in extracellular region. Predicted to be part of laminin complex. Is expressed in blood vessel; brain; neural rod; tail bud; and trunk. Orthologous to human NTN4 (netrin 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Lambert et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001134 | Netrin domain |
| Domain | IPR002049 | Laminin-type EGF domain |
| Domain | IPR008211 | Laminin, N-terminal |
| Domain | IPR018933 | Netrin module, non-TIMP type |
| Domain | IPR035811 | Netrin-4, NTR domain |
| Family | IPR050440 | Laminin/Netrin Extracellular Matrix |
| Homologous_superfamily | IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
Domain Details Per Protein
| Protein | Length | Laminin/Netrin Extracellular Matrix | Laminin, N-terminal | Laminin-type EGF domain | Netrin-4, NTR domain | Netrin domain | Netrin module, non-TIMP type | Tissue inhibitor of metalloproteinases-like, OB-fold |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q32SK8
|
558 | |||||||
|
UniProtKB:A0A0R4IFE9
|
639 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-ntn4 | monoclonal | IgG2a | Mouse |
|
R&D Systems
|
2 |
Plasmids
No data available