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Gene

setd1ba

ID
ZDB-GENE-050309-289
Name
SET domain containing 1B, histone lysine methyltransferase a
Symbol
setd1ba Nomenclature History
Previous Names
  • im:7156157
  • si:dkey-237o15.4
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable RNA binding activity and histone-lysine N-methyltransferase activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in chromosome and nuclear speck. Predicted to be part of Set1C/COMPASS complex. Is expressed in brain; cerebellum; and retinal neural layer. Orthologous to human SETD1B (SET domain containing 1B, histone lysine methyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With setd1ba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder with seizures and language delay 619000
Associated With setd1ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR001214 SET domain
Domain IPR003616 Post-SET domain
Domain IPR024657 COMPASS complex Set1 subunit, N-SET domain
Family IPR037842 Histone-lysine N-methyltransferase SETD1B
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length COMPASS complex Set1 subunit, N-SET domain Histone-lysine N-methyltransferase SETD1B Nucleotide-binding alpha-beta plait domain superfamily Post-SET domain RNA-binding domain superfamily RNA recognition motif domain SET domain
UniProtKB:A0A0R4IPF5 1847
UniProtKB:A3KNY8 283
UniProtKB:Q1LY77 1844
UniProtKB:F1Q6L6 1844
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations