Gene

zfhx3a

ID

ZDB-GENE-050309-237

Name

zinc finger homeobox 3a

Symbol

zfhx3a Nomenclature History

Previous Names

im:7145045
im:7152896 (1)
si:ch73-386h18.1
wu:fb53g09

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in nervous system development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in central nervous system. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human ZFHX3 (zinc finger homeobox 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7145045 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With zfhx3a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
prostate cancer	Alliance	Prostate cancer, somatic	176807

Associated With zfhx3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeobox domain
Domain	IPR003604	Matrin/U1-C-like, C2H2-type zinc finger
Domain	IPR013087	Zinc finger C2H2-type
Homologous_superfamily	IPR009057	Homeobox-like domain superfamily
Homologous_superfamily	IPR036236	Zinc finger C2H2 superfamily

Domain Details Per Protein

Protein	Length	Homeobox, conserved site	Homeobox domain	Homeobox-like domain superfamily	Matrin/U1-C-like, C2H2-type zinc finger	Zinc finger C2H2 superfamily	Zinc finger C2H2-type
UniProtKB:F1Q7K3 InterPro	3356

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Length (nt)	Analysis
mRNA	si:ch73-386h18.1-202 (1) Ensembl	13161 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations