Gene

zfhx3a

ID
ZDB-GENE-050309-237
Name
zinc finger homeobox 3a
Symbol
zfhx3a Nomenclature History
Previous Names
  • im:7145045
  • im:7152896 (1)
  • si:ch73-386h18.1
  • wu:fb53g09
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in prostate cancer. Is expressed in central nervous system. Orthologous to human ZFHX3 (zinc finger homeobox 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With zfhx3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial atrial fibrillation Alliance {Atrial fibrillation 8, susceptibility to} 613055
prostate cancer Alliance Prostate cancer, somatic 176807
spinocerebellar ataxia type 4 Alliance Spinocerebellar ataxia 4 600223
Associated With zfhx3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR003604 Matrin/U1-C-like, C2H2-type zinc finger
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Matrin/U1-C-like, C2H2-type zinc finger Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:F1Q7K3 3356
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations