Gene
rbm8a
- ID
- ZDB-GENE-050306-51
- Name
- RNA binding motif protein 8A
- Symbol
- rbm8a Nomenclature History
- Previous Names
-
- fb34f03
- wu:fb34f03
- zgc:110525 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have mRNA binding activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to U2-type catalytic step 1 spliceosome and exon-exon junction complex. Human ortholog(s) of this gene implicated in thrombocytopenia-absent radius syndrome. Orthologous to human RBM8A (RNA binding motif protein 8A).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110525 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Gangras et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
thrombocytopenia-absent radius syndrome | Alliance | Thrombocytopenia-absent radius syndrome | 274000 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000504 | RNA recognition motif domain |
Domain | IPR033744 | RBM8, RNA recognition motif |
Family | IPR008111 | RNA-binding motif protein 8 |
Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | RBM8, RNA recognition motif | RNA-binding domain superfamily | RNA-binding motif protein 8 | RNA recognition motif domain |
---|---|---|---|---|---|---|
UniProtKB:Q5D018
|
174 |
Interactions and Pathways
No data available
Plasmids
No data available