Gene

rbm8a

ID

ZDB-GENE-050306-51

Name

RNA binding motif protein 8A

Symbol

rbm8a Nomenclature History

Previous Names

fb34f03
wu:fb34f03
zgc:110525 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to U2-type catalytic step 1 spliceosome and exon-exon junction complex. Human ortholog(s) of this gene implicated in thrombocytopenia-absent radius syndrome. Orthologous to human RBM8A (RNA binding motif protein 8A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:110525 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Gangras et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rbm8a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
thrombocytopenia-absent radius syndrome	Alliance	Thrombocytopenia-absent radius syndrome	274000

Associated With rbm8a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR033744	RBM8, RNA recognition motif
Family	IPR008111	RNA-binding motif protein 8
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily