Gene

phf2

ID

ZDB-GENE-050302-10

Name

PHD finger protein 2

Symbol

phf2 Nomenclature History

Previous Names

phf8
im:4200679
wu:fa14c10

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to enable several functions, including histone H3K9 demethylase activity; transcription coactivator activity; and transition metal ion binding activity. Predicted to be involved in negative regulation of rDNA heterochromatin formation; protein demethylation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in kinetochore and nucleolus. Orthologous to human PHF2 (PHD finger protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With phf2 Human Ortholog

No data available

Associated With phf2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019786	Zinc finger, PHD-type, conserved site
Domain	IPR001965	Zinc finger, PHD-type
Domain	IPR003347	JmjC domain
Domain	IPR019787	Zinc finger, PHD-finger
Domain	IPR041070	Jumonji, helical domain
Family	IPR050690	JHDM1 Histone Demethylase
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type