Gene
pkz
- ID
- ZDB-GENE-050301-2
- Name
- protein kinase containing Z-DNA binding domains
- Symbol
- pkz Nomenclature History
- Previous Names
-
- zgc:136657
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Enables left-handed Z-DNA binding activity and protein kinase activity. Predicted to be involved in negative regulation of translation and regulation of translational initiation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including digestive system; eye; heart; musculature system; and pleuroperitoneal region.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 30 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR042371 | Z-binding domain |
| Family | IPR050339 | Cell Cycle and Stress Response Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Cell Cycle and Stress Response Kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily | Z-binding domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5NE14
|
511 | ||||||||
|
UniProtKB:Q5NE12
|
511 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available