Gene

tmx2a

ID

ZDB-GENE-050208-95

Name

thioredoxin-related transmembrane protein 2a

Symbol

tmx2a Nomenclature History

Previous Names

im:7138651 (1)
zgc:172264 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to be involved in cell redox homeostasis. Predicted to localize to integral component of membrane. Is expressed in myotome and somite. Orthologous to human TMX2 (thioredoxin related transmembrane protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7138651 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tmx2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with microcephaly, cortical malformations, and spasticity	618730

Associated With tmx2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013766	Thioredoxin domain
Domain	IPR037463	Thioredoxin-related transmembrane protein 2, thioredoxin domain
Family	IPR039101	Thioredoxin-related transmembrane protein 2
Homologous_superfamily	IPR036249	Thioredoxin-like superfamily