Gene

kntc1

ID
ZDB-GENE-050208-92
Name
kinetochore associated 1
Symbol
kntc1 Nomenclature History
Previous Names
  • im:6912223
  • im:7138629
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable small GTPase binding activity. Predicted to be involved in mitotic sister chromatid segregation; mitotic spindle assembly checkpoint signaling; and protein localization to kinetochore involved in kinetochore assembly. Predicted to be part of RZZ complex. Predicted to be active in cytoplasm and kinetochore microtubule. Orthologous to human KNTC1 (kinetochore associated 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kntc1 Human Ortholog
No data available
Associated With kntc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR019527 RZZ complex, subunit KNTC1/ROD, C-terminal
Domain IPR055402 KNTC1, N-terminal
Domain IPR055403 KNTC1, first ARM-repeats domain
Domain IPR055404 KNTC1, second ARM-repeats domain
Domain IPR055405 KNTC1, third ARM-repeats domain
Family IPR052802 Kinetochore-associated protein 1
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Domain Details Per Protein
Protein Additional Resources Length Kinetochore-associated protein 1 KNTC1, first ARM-repeats domain KNTC1, N-terminal KNTC1, second ARM-repeats domain KNTC1, third ARM-repeats domain RZZ complex, subunit KNTC1/ROD, C-terminal WD40-repeat-containing domain superfamily
UniProtKB:A0A8M3B017 InterPro 2241
UniProtKB:A0A8M9QEY6 InterPro 2232
UniProtKB:A0A8M3ASW0 InterPro 2240
UniProtKB:A0A0R4IHW6 InterPro 2290
UniProtKB:A0AB32TW84 InterPro 2240
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA kntc1-201 (1)
Ensembl
Ensembl 6,873 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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