nuak2

ID

ZDB-GENE-050208-563

Name

NUAK family, SNF1-like kinase, 2

Symbol

nuak2 Nomenclature History

Previous Names

si:rp71-11b17.3

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cellular response to glucose starvation. Human ortholog(s) of this gene implicated in anencephaly. Orthologous to human NUAK2 (NUAK family kinase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nuak2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Anencephaly 2	619452

Associated With nuak2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily