Gene

rdh5

ID
ZDB-GENE-050208-411
Name
retinol dehydrogenase 5 (11-cis/9-cis)
Symbol
rdh5 Nomenclature History
Previous Names
  • hsd17b9 (1)
  • im:6901729
  • si:dkey-102c8.5
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have oxidoreductase activity. Involved in eye photoreceptor cell differentiation; retina development in camera-type eye; and vitamin A biosynthetic process. Predicted to localize to integral component of membrane. Is expressed in several structures, including gut; heart; pineal complex; skeletal muscle cell; and visual system. Human ortholog(s) of this gene implicated in fundus albipunctatus and night blindness. Orthologous to human RDH5 (retinol dehydrogenase 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rdh5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
fundus albipunctatus Alliance Fundus albipunctatus 136880
Associated With rdh5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020904 Short-chain dehydrogenase/reductase, conserved site
Family IPR002347 Short-chain dehydrogenase/reductase SDR
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase, conserved site Short-chain dehydrogenase/reductase SDR
UniProtKB:F1RCW4 328
UniProtKB:Q1LXG1 344
UniProtKB:Q0R680 326
UniProtKB:Q4V8Y1 328
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations