Gene
ankfy1
- ID
- ZDB-GENE-041222-1
- Name
- ankyrin repeat and FYVE domain containing 1
- Symbol
- ankfy1 Nomenclature History
- Previous Names
-
- wu:fb69g03
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable small GTPase binding activity. Predicted to be involved in Golgi to lysosome transport and retrograde transport, endosome to Golgi. Predicted to be active in endosome membrane. Orthologous to human ANKFY1 (ankyrin repeat and FYVE domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa9391 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000210 | BTB/POZ domain |
Domain | IPR000306 | FYVE zinc finger |
Domain | IPR017455 | Zinc finger, FYVE-related |
Domain | IPR049763 | Rabankyrin-5,BTB and C-terminal Kelch domain |
Domain | IPR049764 | Rabankyrin-5, FYVE domain |
Domain | IPR049765 | Rabankyrin-5, BTB/POZ domain |
Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | BTB/POZ domain | FYVE zinc finger | Rabankyrin-5,BTB and C-terminal Kelch domain | Rabankyrin-5, BTB/POZ domain | Rabankyrin-5, FYVE domain | SKP1/BTB/POZ domain superfamily | Zinc finger, FYVE/PHD-type | Zinc finger, FYVE-related | Zinc finger, RING/FYVE/PHD-type |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A0R4IK06 | InterPro | 1167 | |||||||||||
UniProtKB:A2CER9 | InterPro | 1166 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
ankfy1-201
(1)
|
Ensembl | 4,905 nt | ||
mRNA |
ankfy1-202
(1)
|
Ensembl | 3,504 nt | ||
mRNA |
ankfy1-203
(1)
|
Ensembl | 4,898 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-193H7 | ZFIN Curated Data | |
Encodes | EST | fb69g03 |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001102672 (1) | 4905 nt | ||
Genomic | GenBank:CR753844 (1) | 172761 nt | ||
Polypeptide | UniProtKB:A0A0R4IK06 (1) | 1167 aa |
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
- Lo, J., Lee, S., Xu, M., Liu, F., Ruan, H., Eun, A., He, Y., Ma, W., Wang, W., Wen, Z., and Peng, J. (2003) 15,000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Genome research. 13(3):455-466
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