Gene

erg

ID
ZDB-GENE-041212-40
Name
ETS transcription factor ERG
Symbol
erg Nomenclature History
Previous Names
  • erg1 (1)
  • zgc:103429
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in angiogenesis and hemangioblast cell differentiation. Predicted to localize to nucleus. Is expressed in several structures, including angioblastic mesenchymal cell; cardiovascular system; intermediate cell mass of mesoderm; mesoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human ERG (ETS transcription factor ERG).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Liu et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With erg Human Ortholog
No data available
Associated With erg Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000418 Ets domain
Domain IPR003118 Pointed domain
Family IPR035575 Friend leukemia integration 1 transcription factor
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Ets domain Friend leukemia integration 1 transcription factor Pointed domain Sterile alpha motif/pointed domain superfamily Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q5PR65 427
UniProtKB:F1QK28 426
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations