ZFIN ID: ZDB-GENE-041212-40
Gene Name: ETS transcription factor ERG
Gene Symbol: erg    Nomenclature History

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Previous Names: erg1 (1), zgc:103429

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in angiogenesis and hemangioblast cell differentiation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in myeloid leukemia. Is expressed in several structures, including angioblastic mesenchymal cell; cardiovascular system; intermediate cell mass of mesoderm; mesoderm; and pharyngeal arch. Orthologous to human ERG (ETS transcription factor ERG).
Genome Resources: Alliance (1),  Gene:494073 (1),  Ensembl(GRCz11):ENSDARG00000077304 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17564 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31755 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-erg N/A 1
    MO2-erg N/A 1
    MO3-erg N/A 2
    DISEASE ASSOCIATED WITH erg HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH erg VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hemangioblast cell differentiation (more)
    Cellular Component host cell nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM erg No data available
    MARKER RELATIONSHIPS
    erg Contained in: [BAC] CH211-134J13
    erg Encodes: [cDNA] MGC:103429 (1), MGC:192934 (1)
    erg Is Hybridized by: [EST] fa11a02
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001008616 (1) 2811 nt
    Genomic GenBank:CU499177 59339 nt
    Select Tool
    Polypeptide UniProtKB:Q5PR65 (1) 427 aa
    Sequence Information (all 15)
    ORTHOLOGY for erg ( Chr: 10 )
    CITATIONS (32)