Gene

ppat

ID
ZDB-GENE-041210-323
Name
phosphoribosyl pyrophosphate amidotransferase
Symbol
ppat Nomenclature History
Previous Names
  • im:6894693
  • si:dkeyp-117h8.5
  • wu:fb61f03
  • wu:fc28b09
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have amidophosphoribosyltransferase activity; iron-sulfur cluster binding activity; and metal ion binding activity. Predicted to be involved in 'de novo' IMP biosynthetic process; nucleoside metabolic process; and purine nucleobase biosynthetic process. Is expressed in several structures, including alar plate midbrain region; digestive system; nervous system; pectoral fin bud; and segmental plate. Orthologous to human PPAT (phosphoribosyl pyrophosphate amidotransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppat Human Ortholog
No data available
Associated With ppat Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000836 Phosphoribosyltransferase domain
Domain IPR017932 Glutamine amidotransferase type 2 domain
Domain IPR035584 Amidophosphoribosyltransferase, N-terminal
Family IPR005854 Amidophosphoribosyltransferase
Homologous_superfamily IPR029055 Nucleophile aminohydrolases, N-terminal
Homologous_superfamily IPR029057 Phosphoribosyltransferase-like
Domain Details Per Protein
Protein Length Amidophosphoribosyltransferase Amidophosphoribosyltransferase, N-terminal Glutamine amidotransferase type 2 domain Nucleophile aminohydrolases, N-terminal Phosphoribosyltransferase domain Phosphoribosyltransferase-like
UniProtKB:A6H8S4 508
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations