Gene
avpr1ab
- ID
- ZDB-GENE-041210-105
- Name
- arginine vasopressin receptor 1Ab
- Symbol
- avpr1ab Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Enables peptide hormone binding activity. Predicted to be involved in several processes, including cellular response to hormone stimulus; positive regulation of vasoconstriction; and regulation of systemic arterial blood pressure by vasopressin. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in blood vessel endothelium; central nervous system; and head. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human AVPR1A (arginine vasopressin receptor 1A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Vasopressin receptor | Vasopressin V1A receptor | Vasopressin V1 receptor, C-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:F1Q5N3
|
410 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
avpr1ab-201
(1)
|
Ensembl | 5,174 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-125A15 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001297676 (1) | 1315 nt | ||
| Genomic | GenBank:BX255922 (2) | 155429 nt | ||
| Polypeptide | UniProtKB:F1Q5N3 (1) | 410 aa |
- Zanardini, M., Zhang, W., Habibi, H.R. (2024) Arginine Vasotocin Directly Regulates Spermatogenesis in Adult Zebrafish (Danio rerio) Testes. International Journal of Molecular Sciences. 25(12):
- Salahinejad, A., Attaran, A., Meuthen, D., Rachamalla, M., Chivers, D.P., Niyogi, S. (2022) Maternal exposure to bisphenol S induces neuropeptide signaling dysfunction and oxidative stress in the brain, and abnormal social behaviors in zebrafish (Danio rerio) offspring. The Science of the total environment. 830:154794
- Giribaldi, J., Ragnarsson, L., Pujante, T., Enjalbal, C., Wilson, D., Daly, N.L., Lewis, R.J., Dutertre, S. (2020) Synthesis, Pharmacological and Structural Characterization of Novel Conopressins from Conus miliaris. Marine drugs. 18(3):
- Landin, J., Hovey, D., Xu, B., Lagman, D., Zettergren, A., Larhammar, D., Kettunen, P., Westberg, L. (2020) Oxytocin Receptors Regulate Social Preference in Zebrafish. Scientific Reports. 10:5435
- Salahinejad, A., Naderi, M., Attaran, A., Meuthen, D., Niyogi, S., Chivers, D.P. (2020) Effects of chronic exposure to bisphenol-S on social behaviors in adult zebrafish: Disruption of the neuropeptide signaling pathways in the brain. Environmental pollution (Barking, Essex : 1987). 262:113992
- Tang, W., Davidson, J.D., Zhang, G., Conen, K.E., Fang, J., Serluca, F., Li, J., Xiong, X., Coble, M., Tsai, T., Molind, G., Fawcett, C.H., Sanchez, E., Zhu, P., Couzin, I.D., Fishman, M.C. (2020) Genetic Control of Collective Behavior in Zebrafish. iScience. 23:100942
- Tong, S.K., Lee, H.L., Lee, Y.C., Wu, L.C., Tsou, Y.L., Lu, S.W., Shih, S.W., Hwang, P.P., Chou, M.Y. (2020) Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes. International Journal of Molecular Sciences. 21(11)
- Carreño Gutiérrez, H., Colanesi, S., Cooper, B., Reichmann, F., Young, A.M.J., Kelsh, R.N., Norton, W.H.J. (2019) Endothelin neurotransmitter signalling controls zebrafish social behaviour. Scientific Reports. 9:3040
- Page, D.J., Thuret, R., Venkatraman, L., Takahashi, T., Bentley, K., Herbert, S.P. (2019) Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis. Cell Reports. 27:3139-3151.e5
- Ramakrishnan Varadarajan, A., Mopuri, R., Streelman, J.T., McGrath, P.T. (2018) Genome-wide protein phylogenies for four African cichlid species. BMC Evolutionary Biology. 18:1
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