Gene
pygl
- ID
- ZDB-GENE-041205-1
- Name
- phosphorylase, glycogen, liver
- Symbol
- pygl Nomenclature History
- Previous Names
-
- zgc:66314
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable glycogen phosphorylase activity and pyridoxal phosphate binding activity. Predicted to be involved in glycogen catabolic process. Predicted to be active in cytoplasm. Is expressed in eye; heart; kidney; liver; and muscle. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease VI; and lactic acidosis. Orthologous to human PYGL (glycogen phosphorylase L).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| glycogen storage disease VI | Alliance | Glycogen storage disease VI | 232700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Glycogen/starch/alpha-glucan phosphorylase | Glycosyl transferase, family 35 | Phosphorylase pyridoxal-phosphate attachment site |
|---|---|---|---|---|---|
| UniProtKB:Q5RKM9 | InterPro | 967 | |||
| UniProtKB:A0AB13A8T7 | InterPro | 854 |
Interactions and Pathways
No data available
Plasmids
No data available