ZFIN is now using GRCz12tu for Genomic Data
Gene
lcp2a
- ID
- ZDB-GENE-041114-97
- Name
- lymphocyte cytosolic protein 2a
- Symbol
- lcp2a Nomenclature History
- Previous Names
-
- wu:fj47a12
- zgc:101809
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway; intracellular signal transduction; and mast cell activation. Predicted to be located in cytosol. Predicted to be part of TCR signalosome. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 81. Orthologous to human LCP2 (lymphocyte cytosolic protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 81 | Alliance | Immunodeficiency 81 | 619374 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoreceptor signaling adapters | SH2 domain | SH2 domain superfamily | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B875 | InterPro | 510 | |||||
| UniProtKB:A0A8M2B8A4 | InterPro | 502 | |||||
| UniProtKB:Q8JI36 | InterPro | 501 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers