Gene

sugt1

ID

ZDB-GENE-041114-56

Name

SGT1 homolog, MIS12 kinetochore complex assembly cochaperone

Symbol

sugt1 Nomenclature History

Previous Names

sgut1
wu:fd45a02
zgc:103668 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to enable protein-folding chaperone binding activity. Predicted to be located in cytoplasm. Orthologous to human SUGT1 (SGT1 homolog, MIS12 kinetochore complex assembly cochaperone).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6906664 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa1200	Allele with one point mutation	Unknown	Splice Site	ENU
sa25589	Allele with one point mutation	Unknown	Splice Site	ENU

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Sequence Targeting Reagents

No data available

Human Disease

Associated With sugt1 Human Ortholog

No data available

Associated With sugt1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR007052	CS domain
Domain	IPR007699	SGS domain
Family	IPR044563	Protein Sgt1-like
Homologous_superfamily	IPR008978	HSP20-like chaperone
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily

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Domain Details Per Protein

Protein	Additional Resources	Length	CS domain	HSP20-like chaperone	Protein Sgt1-like	SGS domain	Tetratricopeptide-like helical domain superfamily	Tetratricopeptide repeat
UniProtKB:A0A8M9Q3V2	InterPro	215
UniProtKB:Q5U3E4	InterPro	322

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Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 1

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	sugt1-202 (1) Ensembl	Ensembl	640 nt	Select Tool ZFIN BLAST
mRNA	sugt1-203 (1) Ensembl	Ensembl	1,580 nt	Select Tool ZFIN BLAST
mRNA	sugt1-205 (1) Ensembl	Ensembl	2,557 nt	Select Tool ZFIN BLAST
ncRNA	sgut1-003 (1) Ensembl	Ensembl	668 nt	Select Tool ZFIN BLAST
ncRNA	sgut1-004 (1) Ensembl	Ensembl	633 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	CH73-80P9	CU915815	ZFIN Curated Data
Contained in	BAC	CH211-278I5	BX936424	ZFIN Curated Data
Encodes	EST	fd45a02	AW019686 BF717372
Encodes	EST	IMAGE:6906664	CB363409	Thisse et al., 2004
Encodes	cDNA	MGC:103668	BC085582	ZFIN Curated Data
Encodes	cDNA	MGC:173754	BC152151	ZFIN Curated Data
Encodes	cDNA	MGC:191525	BC164350	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001007361 (1)	1566 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX936424	162683 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q5U3E4 (1)	322 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	SUGT1	13	Ensembl:ENSG00000165416 Gene:10910 HGNC:16987 OMIM:604098	Amino acid sequence comparison (1)
Mouse	Sugt1	14	Ensembl:ENSMUSG00000022024 Gene:67955 MGI:1915205	Amino acid sequence comparison (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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