Gene

ppm1db

ID
ZDB-GENE-041114-27
Name
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
Symbol
ppm1db Nomenclature History
Previous Names
  • zgc:103518 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have magnesium-dependent protein serine/threonine phosphatase activity and mitogen-activated protein kinase binding activity. Predicted to be involved in protein dephosphorylation. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppm1db Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
breast cancer Alliance Breast cancer, somatic 114480
Jansen de Vries syndrome 617450
Associated With ppm1db Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000222 PPM-type phosphatase, divalent cation binding
Domain Details Per Protein
Protein Length PPM-type phosphatase, divalent cation binding
UniProtKB:A0A2R8RM47 534
UniProtKB:Q5U3H7 534
UniProtKB:A2ATY1 534
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations