Gene
kmt5b
- ID
- ZDB-GENE-041114-22
- Name
- lysine methyltransferase 5B
- Symbol
- kmt5b Nomenclature History
- Previous Names
-
- suv420h1 (1)
- wu:fb97g06
- wu:fi57g03
- zgc:103527
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Enables histone H4K20 methyltransferase activity. Acts upstream of or within regulation of growth. Predicted to be located in chromosome. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 51. Orthologous to human KMT5B (lysine methyltransferase 5B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103527 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 51 | Alliance | Intellectual developmental disorder, autosomal dominant 51 | 617788 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001214 | SET domain |
| Domain | IPR044424 | KMT5B , SET domain |
| Family | IPR025790 | Suv4-20 family, animal |
| Family | IPR039977 | Histone-lysine N-methyltransferase Suv4-20/Set9 |
| Homologous_superfamily | IPR041938 | Histone-lysine N-methyltransferase, N-terminal domain |
| Homologous_superfamily | IPR046341 | SET domain superfamily |
Domain Details Per Protein
| Protein | Length | Histone-lysine N-methyltransferase, N-terminal domain | Histone-lysine N-methyltransferase Suv4-20/Set9 | KMT5B , SET domain | SET domain | SET domain superfamily | Suv4-20 family, animal |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5U3H2
|
808 |
Interactions and Pathways
No data available
Plasmids
No data available